Programme
Tuesday, 5 September, 2006
9:00-18:00 Common registration for ELIFE and ICBL
12:00-13:00 Lunch for ELIFE participants
13:00-14:00 ELIFE Working Group - progress reports and business meeting for group leaders
14:00-16:00 ELIFE workshop on "Lipidomics and Health" (Organizers: Balázs Sarkadi and András Váradi)
| 14:00-14:30 | Gerrit van Meer, Balázs Sarkadi: Introduction and welcome |
| 14:30-15:00 | Gerd Utermann: Genetic background of lipid disorders |
| 15:00-15:30 | Jürgen Borlak: Aberrant lipid metabolism in human diseases - The role of the Lectin like oxidised LDL-receptor (LOX-1) in endothelial dysfunction |
| 15:30-16:00 | Balázs Sarkadi: ABC transporters for membrane lipids |
16:00-16:30 Coffee/Tea Break
16:30-17:30 ELIFE - ISSFAL joint session: Lipidomics and Health
| 16:30-17:00 | Hee-Yong Kim: Lipidomics of the Brain: Application of Mass Spectrometry in Membrane-Related Signaling Research |
| 17:00-17:30 | Philippe Bougnoux: Diet, cancer and the lipidome |
18:00-18:50 Opening Ceremony of ICBL
| 18:00-18:05 | Opening talks: László Vígh (Chairman) and Fritz Spener (Past president of ICBL |
| 18:05-18:20 | In memoriam Tibor Farkas: John E. Halver (US National Academy of Sciences) |
| 18:20-18:45 | Hungarian folk dance |
| 18:45-18:50 | Michel Lagarde(Present president of ICBL) |
18:50-19:30 The Laurens van Deenen Lecture
- Ben de Kruijff: Membranes, where lipids and proteins meet
19:45 Welcome reception for ELIFE and ICBL attenders
Wednesday, 6 September, 2006
Joint sessions with ELIFE
Lipidomics (Gerd Schmitz, Gábor Balogh)
9:00-10:45 Plenary lectures
| 9:00-9:35 | Markus Wenk: Lipidomics of host-pathogen interactions |
| 9:35-10:10 | Edward A. Dennis: LIPID MAPS and Eicosanoid Lipidomics |
| 10:10-10:45 | Gerd Schmitz: Effects of the Differential Raft Regulation During Ox-LDL and E-LDL Loading in Human Macrophages |
10:45-11:15 Coffee/Tea Break
11:15-12:30 Oral communications selected from submitted abstracts
| 11:15-11:40 | Gerhard Liebisch: Metabolic profiling of glycerophospholipid synthesis in fibroblasts loaded with free cholesterol and modified low density lipoproteins |
| 11:40-12:05 | Tatjana Becker: Identification of lipolytic enzymes and their potential role in the cholesterol homeostasis of murine macrophages |
| 12:05-12:30 | Karl Lohner: Cytoplasmic Membrane Lipids Modulate the Mode of Membrane Perturbation of Antimicrobial Peptides |
12:30-13:40 Lunch
13:40-14:30 Poster (I) Viewing
Membrane microdomains: lipid rafts and caveolae (Gerrit van Meer, János Szöllősi)
14:30-16:30 Plenary lectures
| 14:30-15:00 | János Szöllősi: Membrane microdomains: distinct molecular association clusters from a functional point of view |
| 15:00-15:30 | Gerhard Schütz: A Close Look onto the Nanoscopic Organization of the Plasma Membrane using Single Molecule Microscopy |
| 15:30-16:00 | Akihiro Kusumi: Paradigm shift of the plasma membrane concept from the two-dimensional continuum fluid to the partitioned fluid |
| 16:00-16:30 | Gerrit van Meer: Dynamic organization and unexpected function of typical raft lipids |
16:30-17:00 Coffee/Tea Break
17:00-18:10 Oral communications selected from submitted abstracts
| 17:00-17:25 | Wim J. van Blitterswijk: Apoptosis Resistance to FAS/CD95 ligation and to Alkyl-lysophospholipid due to Sphingomyelin Synthase 1 Deficiency |
| 17:25-17:50 | Toshihide Kobayashi: Combination of Different Cholesterol Probes Reveal the Cholesterol Gradient in Cell Membranes |
| 17:50-18:10 | Evelyn Orsó: The cholesterol absorption inhibitor Ezetimib disrupts raft-microdomains and influences CD13-dependent cellular lipid metabolism in human monocytes/macrophages |
19:00 Reception (cheese and wine), by the Deputy Mayor of Pécs and Sándor Damjanovich (President of Division of Biology, Hungarian Academy of Sciences)
Thursday, 7 September, 2006
9:00-10:00 In memoriam Tibor Farkas (Fritz Spener)
| 9:00-9:30 | Michael Schlame: Barth Syndrome, a Human Disorder of Cardiolipin Metabolism |
| 9:30-10:00 | Pablo Escriba: Membrane-lipid therapy |
Lipids and stress (John Harwood, László Vígh)
10:00-11:00 Plenary lectures
| 10:00-10:30 | John Zehmer: Thermal acclimation in raft microdomains of the plasma membrane |
| 10:30-11:00 | John Harwood: A novel desaturase involved in stress adaptation in the soil protozoon, Acanthamoeba castellanii |
11:00-11:20 Coffee/Tea Break
11:20-12:20 Plenary lectures
| 11:20-11:50 | Ibolya Horváth: Stress protein responses in mammalian cells under the control of lipid composition and microdomain organization of membranes |
| 11:50-12:20 | George M. Carman: Regulation of the yeast Mg2+-dependent phosphatidate phosphatase in response to nutrient deprivation |
12:20-13:30 Lunch
13:30-14:30 Oral communications selected from submitted abstracts
| 13:30-13:50 | Pauli Juhani Ojala: Lipids Transcriptomics metaanalysis of the lysophospholipid 7-TMS receptors |
| 13:50-14:10 | Panos Kourounakis: New Derivatives of Nonsteroidal Anti-inflammatory Drugs (NSAIDs) with Hypolipidemic and Antioxidant Properties |
| 14:10-14:30 | Arthur Spector: Epoxyeicosatrienoic Acid (EET) Utilization in Kidney Tubular Epithelial Cells: Effect of Soluble Epoxide Hydrolase Inhibition |
14:30-15:30 Hot topics
| 14:30-15:00 | Thomas Haines: A Possible Role for the Polyunsaturated Fatty Acids in the Rhodopsin-to-Transducin Signal |
| 15:00-15:30 | Stefano Piotto: Modelling of lipid membranes and membrane interacting compounds |
15:30-17:00 Poster (I) viewing
18:00 Wine tasting and dinner in Villány at a famous vineyard
Friday, 8 September, 2006
Gene regulation by nucleus-targeted lipid signaling system (Bart Staels, Ibolya Horváth)
9:00-10:45 Plenary lectures
| 9:00-9:35 | Folkert Kuipers: Regulation of lipid metabolism by the nuclear receptors LXR and FXR |
| 9:35-10:10 | Niko Marx: Cardiovascular effects of PPAR activators |
| 10:10-10:45 | Bart Staels: Nuclear Receptors as Therapeutic Targets to Modulate the Metabolic Syndrome |
10:45-11:15 Coffee/Tea break
11:15-12:30 Oral communications selected from submitted abstracts
| 11:15-11:40 | Harini Sampath: Stearoyl CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat |
| 11:40-12:05 | Anders Jacobsson: Role of the fatty acid elongase ELOVL3 in brown adipose tissue |
| 12:05-12:30 | Maurizio Crestani: Analysis of nuclear factors dynamically exchanged on the cholesterol 7a-hydroxylase gene reveals a target for treatment of hypercholesterolemia |
12:30-14:00 Lunch
14:00-19:00 Registration of ILPS attenders (ILPS organizers: Willem van Nieuwenhuyzen, Michael Schneider)
What are healthy lipids? (Pablo Escriba, Győző Garab)
14:00-15:45 Plenary lectures
| 14:00-14:35 | Ingeborg Brouwer: N-3 Fatty Acids And Cardiac Arrhythmia |
| 14:35-15:10 | Bengt Vessby: Health effects of Conjugated Linoleic Acid (CLA) |
| 15:10-15:45 | Gwendolyn Barcelo-Coblijn: Beneficial effects of alpha-linoleic acid enriched diets: From animal model to a human trial |
15:45-17:15 Coffee/Tea break and Poster (II) viewing
18:00 Meeting of the ICBL Steering Committee
19:00 Opening mixer for ILPS attenders
Saturday, 9 September, 2006
Joint sessions with ILPS
8:50-09:00 ILPS Opening
Metabolism and function of lipids in the brain (Norman Salem, Klára Kitajka)
9:00-11:00 Plenary lectures
| 9:00-9:30 | Norman Salem: Function and metabolism of docosahexaenoic acid in the nervous system: Where does it come from and what does it do? |
| 9:30-10:00 | Thomas Brenna: The influence of perinatal long chain polyunsaturate nutrition and prematurity on neural tissue polyunsaturate composition and function studied in non-human primates |
| 10:00-10:30 | Sylvie Chalon: Effects of EFAs on brain function: the contribution of animal models |
| 10:30-11:00 | László Puskás: Protein microarrays for dietary lipid-induced expression analysis in the brain |
11:00-11:20 Coffee/Tea Break
11:20-11:50 Plenary lecture
| 11:20-11:50 | Andrew Sinclair: Will the relationship between "long chain PUFA and brain" ever achieve the same status as the "calcium and bone" relationship? |
11:50-12:30 Oral communications selected from submitted abstracts
| 11:50-12:10 | Benjamin Buaud: Effects of a n-3 polyunsaturated fatty acid deficiency on the expression of nuclear receptors and synaptic plasticity markers in rat brain |
| 12:10-12:30 | Jérémy Skrzypski: PUFA metabolism in rat brain in relation to aging: influence of n-3 dietary fatty acids |
12:30-13:30 Lunch
13:30-14:30 Poster (II) Viewing
Sphingolipids (Yoshitaka Nagai, Yasuyuki Igarashi)
14:30-16:00 Plenary lectures
| 14:30-15:00 | Yoshio Hirabayashi: Roles of glycosphingolipid synthesis in brain development and survival |
| 15:00-15:30 | Tony Futerman: LASS genes: mammalian ceramide synthases |
| 15:30-16:00 | Gábor Tigyi: Ligand Design to Lysophospholipid Receptors by Validated Computational Models |
16:00-16:35 Coffee/Tea Break
16:35-17:35 Plenary lectures
| 16:35-17:05 | Howard Riezman: Synthesis, Transport, and Function of Ceramides in Yeast |
| 17:05-17:35 | Yasuyuki Igarashi: Topological metabolism and transbilayer dynamics of sphingolipids |
17:35-18:00 Oral communication selected from submitted abstracts
| 17:35-18:00 | Makoto Ito: Biological Significance of Ceramide Metabolism in Development of Nervous and Vascular Systems in Zebrafish |
18:00-18:30 Presentation of ICBL 2007 and Closing ceremony
19:30 Conference dinner and announcement of 'Poster' and 'BBA Young Speaker' awards (together with ILPS attenders)
Sunday, 10 September, 2006
Additional 1-day session of ILPS
Sphingolipids II (Ĺke Nilsson)
9:00-11:00 Plenary lectures and oral communications
| 9:00-9:30 | Ĺke Nilsson: Sphingolipid metabolism in the gut. Which are the important issues? |
| 9:30-10:00 | Peter Slotte: Interactions between sphingomyelin and cholesterol in cells |
| 10:00-10:30 | Erich Gulbins: Ceramide-enriched membrane domains in infectious biology |
| 10:30-11:00 | Willem F. Nieuwenhuizen: Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice |
11:00-11:30 Coffee/Tea Break and Poster (II) Viewing
11:30-12:30 Plenary lectures and oral communications
| 11:30-12:00 | Rui-Dong Duan: Sphingomyelinases and Ceramidases in the Intestinal Mucosa |
| 12:00-12:30 | Karel van Erpecum: Influence of bile salts on molecular interactions between sphingomyelin and cholesterol: relevance for biliary and intestinal tract |
12:30-14:00 Lunch and Poster (II) Viewing
Marine Phospholipids (Michael Schneider)
14:00-16:00 Plenary lectures and oral communications
| 14:00-14:30 | Erik Lovaas: Marine Phospholipids (MPL): The third generation of omega-3 products |
| 14:30-15:00 | Joseph Hibbeln: Omega-3 fatty acids in aggression and depression |
| 15:00-15:30 | Hee-Yong Kim: Phosphatidylserine in Neuronal Signaling |
| 15:30-16:00 | Dori Pelled: Omega-3 phosphatidylserine - Effect on cognitive performance and attention deficit hyperactivity disorder (ADHD) |
16:00-16:30 Coffee/Tea Break and Poster (II) Viewing
16:30-17:30 Plenary lectures and oral communications
| 16:30-17:00 | Maud Cansell: Comparison of the metabolic fate of n-3 PUFA in plasma and liver of rats supplemented with marine lipid-based liposomes or fish oil |
| 17:00-17:30 | Hogne Hallaraker: Enzymatically transesterified phospholipids: Transesterification of the fatty acids in soy phospholipids to produce marine phospolipids and their effects in animal models |
17:30-17:45 Closing Session of ILPS Congress